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Clinical Research Publications and Presentations

Laquer VT, Hevezi PA, Albrecht H, Chen TS, Zlotnik A, Kelly KM. Microarray analysis of port wine stains before and after pulsed dye laser treatment. Lasers Surg Med. 2013 Feb;45(2):67-75.

Laquer VT, Dao BM, Pavlis JM, Nguyen AN, Chen TS, Harris RM, Rugg EL, Kelly KM. Immunohistochemistry of angiogenesis mediators before and after pulsed dye laser treatment of angiomas. Lasers Surg Med. 2012 Mar;44(3):205-10.

Laquer V, Kelly KM, Dao B, Marshall J, Nguyen A, Chen T, Harris R, Rugg E. Angiogenesis Mediator Alterations in Angiomas After Pulsed Dye Laser Treatment. Cutaneous Laser Surgery section for the 31st American Society for Laser Medicine and Surgery Conference, March 30 - April 3, 2011.

Fife D, Rayhan DJ, Behnam S, Ortiz A, Elkeeb L, Aquino L, Eduardo Roa D, Ramsinghani N, Kuo J, Newcomb R, Zachary CB, Kelly KM. A Randomized, Controlled, Double-Blind Study of Light Emitting Diode Photomodulation for the Prevention of Radiation Dermatitis in Patients with Breast Cancer. Dermatol Surg 2010 Dec;36(12):1921-7.

Tremaine AM, Ortiz AE, Elkeeb L, Tran M, Weinstein G. Long-term Efficacy and Safety of Topical PRK 124 (0.125%) Lotion (Pyratine-XR) in the Treatment of Mild-to-Moderate Rosacea. J Drugs Dermatol. 2010 Jun;9(6): 647-650.

Ortiz AE, Tremaine AM, Zachary CB. Long-term efficacy of a fractional resurfacing device. Laser Surg Med. 2010 Feb;42(2): 168-70.

Tremaine A, Ortiz A, Zachary C, and the Five-Year Study Group. Long-term (5 Year) Polymethylmethacrylate Microsphere Soft Tissue Filler Safety & Patient Satisfaction Study: 18-Month Interim Analysis. Poster presented at 2010 Hawaii Derm Seminar. Feb  13–19, 2010. Big Island, HI.

Tremaine A, Ortiz A, Armstrong J, Huang Y, Elkeeb L, Choi B, Kelly K. Combined Therapy for Enhanced Microvascular Destruction in Port Wine Stains: Pulsed Dye Laser Photothermolysis and Imiquimod. Data presented at the American Society for Laser Medicine and Surgery 2009 Annual Conference in Washington, DC.

Ortiz A, Elkeeb L, Truitt A, Hindiyeh R, Aquino L, Tran M, Weinstein G. Topical PRK 124 (0.125%) lotion for improving the signs and symptoms of rosacea.
J Drugs Dermatol. 2009 May;8(5):459-62.

Walgrave SE, Ortiz AE, MacFalls HT, Elkeeb L, Truitt AK, Tournas JA, Zelickson BD, Zachary CB.  Evaluation of a novel fractional resurfacing device for treatment of acne scarring.  Lasers Surg Med. 2009 Feb;41(2):122-7.

Rahman Z, MacFalls H, Jiang K, Chan KF, Kelly K, Tournas J, Stumpp OF, Bedi V, Zachary C.  Fractional deep dermal ablation induces tissue tightening.  Lasers Surg Med. 2009 Feb;41(2):78-86.

Ortiz AE, Tremaine AM, Zachary C. Long-term efficacy with a fractional resurfacing device. American Society for Laser Medicine and Surgery Annual Conference, Gaylord National, Washington DC April 2-5, 2009.

Tremaine AM, Ortiz AE, Armstrong J,  Elkeeb L, Huang Y, Choi B, Kelly K. Combined therapy for enhanced microvascular destruction in port wine stains: pulsed dye laser photothermolysis and imiquimod . American Society for Laser Medicine and Surgery Annual Conference, Gaylord National, Washington DC April 2-5, 2009.

Ortiz AE, Tremaine AM, Elkeeb L, Zachary C.  Long-term efficacy and safety of topical PRK 124 (0.125%) lotion (Pyratine-XR) for improving the signs and symptoms of rosacea.  American Academy of Dermatology 67th Annual Conference;  San Francisco, Ca March 8,2009.

Ortiz AE, Tremaine AM, Zachary C.  Long-term efficacy of a fractional resurfacing device. International Society of Cosmetic and Laser Surgeons Annual Conference, Firesky Resort, Scottsdale, AZ Feb 19-22, 2009.

McCullough JL, Garcia RL, Reece B.  A clinical study of topical Pyratine 6 for improving the appearance of photo-damaged skin.  J Drugs Dermatol. 2008 Feb;7(2):131-5.

Fife D, Behnam S, Elkeeb L, Ortiz A, Rayhan D, Aquino L, Roa E, Ramsinghani N, Kuo J, Zachary C, Kelly KM.  LED photo-modulation for prevention of radiation dermatitis:  a prospective, randomized, controlled study.  Poster presented at the American Society for Laser Medicine and Surgery Annual Meeting, 2008.

Hoffman N, Choi B, Kelly KM.  Vascular effects of bevacizumab and pulsed dye laser protocols.  Presented at the American Society for Laser Medicine and Surgery Annual Meeting, 2008.

Ortiz A, Elkeeb L, Truitt A, Tournas J, and Zachary C. Evaluation of a novel fractional resurfacing device for treatment of acne scarring. American Society for Laser Medicine and Surgery Annual Conference, Gaylord Palms, Kissimmee, Florida April 2-6, 2008.

Ortiz AE, Elkeeb LM, Truitt AK, Weinstein GD. Effects of PRK 124 (0.124%) lotion in acne rosacea. International Investigative Dermatology Conference; Kyoto International Conference Center, Kyoto, Japan May 14-17, 2008. Poster 361.

Wu JJ, Weinstein GD, Kricorian GJ, Kormeili T, McCullough JL.  Topical kinetin 0.1% lotion for improving the signs and symptoms of rosacea.  Clin Exp Dermatol. 2007 Nov;32(6):693-5. Epub 2007 Sep 14.

Fife DJ, Behnam S, Rayhan D, Elkeeb L, Ramsinghani N, Kuo J, Kelly K, Roa DE, Truitt A, Zachary C. LED photo-modulation for prevention of post-radiation dermatitis:  A prospective, randomized, controlled study.  Presented at the American Society of Dermatologic Surgery Annual Meeting, 2007.

Truitt A, Echague A, Zachary C, Kelly KM.  Evaluation of the Candela 1064 nm Nd:YAG laser for cellulite and skin tightening.  Presented at the American Society for Laser Medicine and Surgery Annual Meeting, 2007.

Channual JC, Choi B, Pattanachinda D, Lotfi J, Kelly KM.   Long-term vascular effects of photodynamic and pulsed dye laser protocols.  Presented at the American Society for Laser Medicine and Surgery Annual Meeting, 2007.

Menter A, Feldman SR, Weinstein GD, Papp K, Evans R, Guzzo C, Li S, Dooley LT,

Arnold C, Gottlieb AB.  A randomized comparison of continuous vs. intermittent infliximab maintenance regimens over 1 year in the treatment of moderate-to-severe plaque psoriasis.  J Am Acad Dermatol. 2007 Jan;56(1):31.e1-15. Epub 2006 Sep 6.

Tournas JA, Choi B, Kelly KM.  Combined photodynamic and pulsed dye laser treatment of port wine stains.  Presented at the American Society for Laser Medicine and Surgery Annual Meeting, 2006.

Meshkinpour A, Ghasri P, Pope K, Lyubovitsky JG, Risteli J, Krasieva TB, Kelly KM.  Treatment of hypertrophic scars and keloids with a radiofrequency device: a study of collagen effects.  Lasers Surg Med. 2005 Dec;37(5):343-9.

Piacquadio DJ, Chen DM, Farber HF, Fowler JF Jr, Glazer SD, Goodman JJ, Hruza LL, Jeffes EW, Ling MR, Phillips TJ, Rallis TM, Scher RK, Taylor CR, Weinstein GD. Photodynamic therapy with aminolevulinic acid topical solution and visible blue light in the treatment of multiple actinic keratoses of the face and scalp: investigator-blinded, phase 3, multicenter trials.  Arch Dermatol. 2004 Jan;140(1):41-6.

Kelly KM, Svaasand LO, Nelson JS.  Further investigation of pigmentary changes after alexandrite laser hair removal in conjunction with cryogen spray cooling. Dermatol Surg. 2004 Apr;30(4 Pt 1):581-2.

Gottlieb AB, Matheson RT, Lowe N, Krueger GG, Kang S, Goffe BS, Gaspari AA, Ling M, Weinstein GD, Nayak A, Gordon KB, Zitnik R.  A randomized trial of etanercept as monotherapy for psoriasis.  Arch Dermatol. 2003 Dec;139(12):1627-32; discussion 1632.

Weinstein GD, Koo JY, Krueger GG, Lebwohl MG, Lowe NJ, Menter MA, Lew-Kaya DA, Sefton J, Gibson JR, Walker PS.  Tazarotene Cream Clinical Study Group. Tazarotene cream in the treatment of psoriasis: Two multicenter, double-blind, randomized, vehicle-controlled studies of the safety and efficacy of tazarotene creams 0.05% and 0.1% applied once daily for 12 weeks.  J Am Acad Dermatol. 2003 May;48(5):760-7.

 Meshkinpour A, Sun J, Weinstein G.  An open pilot study using tacrolimus ointment in the treatment of seborrheic dermatitis.  J Am Acad Dermatol. 2003 Jul;49(1):145-7. 

Chang CJ, Kelly KM, Van Gemert MJ, Nelson JS.  Comparing the effectiveness of 585-nm vs 595-nm wavelength pulsed dye laser treatment of port wine stains in conjunction with cryogen spray cooling.  Lasers Surg Med. 2002;31(5):352-8.

Kang S, Leyden JJ, Lowe NJ, Ortonne JP, Phillips TJ, Weinstein GD, Bhawan J, Lew-Kaya DA, Matsumoto RM, Sefton J, Walker PS, Gibson JR. Tazarotene cream for the treatment of facial photodamage: a multicenter, investigator-masked, randomized, vehicle-controlled, parallel comparison of 0.01%, 0.025%, 0.05%, and 0.1% tazarotene creams with 0.05% tretinoin emollient cream applied once daily for 24 weeks.  Arch Dermatol. 2001 Dec;137(12):1597-604.

Jeffes EW, McCullough JL, Weinstein GD, Kaplan R, Glazer SD, Taylor JR. Photodynamic therapy of actinic keratoses with topical aminolevulinic acid hydrochloride and fluorescent blue light.  J Am Acad Dermatol. 2001 Jul;45(1):96-104.

Lebwohl MG, Breneman DL, Goffe BS, Grossman JR, Ling MR, Milbauer J, Pincus SH, Sibbald RG, Swinyer LJ, Weinstein GD, Lew-Kaya DA, Lue JC, Gibson JR, Sefton J.  Tazarotene 0.1% gel plus corticosteroid cream in the treatment of plaque psoriasis.  J Am Acad Dermatol. 1998 Oct;39(4 Pt 1):590-6.

Ling MR, Swinyer LJ, Jarratt MT, Falo L, Monroe EW, Tharp M, Kalivas J, Weinstein GD, Asarch RG, Drake L, Martin AG, Leyden JJ, Cook J, Pariser DM, Pariser R, Thiers BH, Lebwohl MG, Babel D, Stewart DM, Eaglstein WH, Falanga V, Katz HI, Bergfeld WF, Hanifin JM, Young MR, et al. Once-weekly fluconazole (450 mg) for 4, 6, or 9 months of treatment for distal subungual onychomycosis of the toenail.  J Am Acad Dermatol. 1998 Jun;38(6 Pt 2):S95-102.

Krueger GG, Drake LA, Elias PM, Lowe NJ, Guzzo C, Weinstein GD, Lew-Kaya DA, Lue JC, Sefton J, Chandraratna RA. The safety and efficacy of tazarotene gel, a topical acetylenic retinoid, in the treatment of psoriasis.  Arch Dermatol. 1998 Jan;134(1):57-60.

Olsen EA, Katz HI, Levine N, Nigra TP, Pochi PE, Savin RC, Shupack J, Weinstein GD, Lufrano L, Jou HC. Sustained improvement in photo-damaged skin with reduced tretinoin emollient cream treatment regimen: effect of once-weekly and three-times-weekly applications. J Am Acad Dermatol. 1997 Aug;37(2 Pt 1):227-30.

Weinstein GD, Krueger GG, Lowe NJ, Duvic M, Friedman DJ, Jegasothy BV, Jorizzo JL, Shmunes E, Tschen EH, Lew-Kaya DA, Lue JC, Sefton J, Gibson JR, Chandraratna RA. Tazarotene gel, a new retinoid, for topical therapy of psoriasis: vehicle-controlled study of safety, efficacy, and duration of therapeutic effect.  J Am Acad Dermatol. 1997 Jul;37(1):85-92.

Jeffes EW, McCullough JL, Weinstein GD, Fergin PE, Nelson JS, Shull TF, Simpson KR, Bukaty LM, Hoffman WL, Fong NL.  Photodynamic therapy of actinic keratosis with topical 5-aminolevulinic acid.  A pilot dose-ranging study. Arch Dermatol. 1997 Jun;133(6):727-32.

Neev J, Nelson JS, Critelli M, McCullough JL, Cheung E, Carrasco WA, Rubenchik AM, Da Silva LB, Perry MD, Stuart BC.  Ablation of human nail by pulsed lasers. Lasers Surg Med. 1997;21(2):186-92.

Monk BJ, Brewer C, VanNostrand K, Berns MW, McCullough JL, Tadir Y, Manetta A. Photodynamic therapy using topically applied dihematoporphyrin ether in the treatment of cervical intraepithelial neoplasiaGynecol Oncol. 1997 Jan;64(1):70-5.

Weinstein GD. Safety, efficacy and duration of therapeutic effect of tazarotene used in the treatment of plaque psoriasis.  Br J Dermatol. 1996 Oct;135 Suppl 49:32-6.

Fehr MK, Chapman CF, Krasieva T, Tromberg BJ, McCullough JL, Berns MW, Tadir Y.  Selective photosensitizer distribution in vulvar condyloma acuminatum after topical application of 5-aminolevulinic acid.  Am J Obstet Gynecol. 1996 Mar;174(3):951-7.

Jeffes EW 3rd, Lee GC, Said S, Sabahi M, McCullough JL, Herrod R, Alzona CP, Linden KG, Soundararajan D, Edwards S, et al.  Elevated numbers of proliferating mononuclear cells in the peripheral blood of psoriatic patients correlate with disease severity. J Invest Dermatol. 1995 Dec;105(6):733-8.

Green LJ, McCormick A, Weinstein GD.  Photo-aging and the skin. The effects of tretinoin. Dermatol Clin. 1993 Jan;11(1):97-105.

Weinstein GD, Nigra TP, Pochi PE, Savin RC, Allan A, Benik K, Jeffes E, Lufrano L, Thorne EG. Topical tretinoin for treatment of photo-damaged skin.  A multicenter study.  Arch Dermatol. 1991 May;127(5):659-65.

Nelson JS, McCullough JL, Glenn TC, Wright WH, Liaw LH, Jacques SL. Mid-infrared laser ablation of stratum corneum enhances in vitro percutaneous transport of drugs.  J Invest Dermatol. 1991 Nov;97(5):874-9.

Weinstein GD, McCullough JL, Olsen E. Topical methotrexate therapy for psoriasis.  Arch Dermatol. 1989 Feb;125(2):227-30.

Weinstein GD. Oral and Topical Cyclosporine Therapy for Psoriasis.  West J Med. 1989 Dec;151(6):651-652.